Mitoquinone mesylate (MitoQ)

This molecule is a synthetic analogue of the antioxidant CoQ10. It was developed and patented by Drs. Robin Smith and Michael Murphy of the University of Otago, New Zealand.

This molecule has an attached lipophilic phosphonium cation, triphenylphosphonium, via an alkyl chain. This formulation significantly enhances targeting and accumulation in mitochondria (mediated by the membrane potential).

MitoQ preferentially accumulates in tissues such as the heart, brain, skeletal muscle, liver, and kidneys that are rich in mitochondria. MitoQ neutralizes free radicals inside the cell. MitoQ thus supports mitochondrial health by reducing the accumulation of deleterious ROS.

MitoQ is available as an oral supplement. A related compound is Mitoquinol that is formulated as a cream for topical applications. The company, MitoQ Ltd indicates there are 7 different MitoQ supplements for internal use as well as a range of skin creams.

We recommend this as an antioxidant to help boost MitoHealth.

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