Probiotics

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Probiotics are living organisms that when consumed provide health benefits through boosting of good get microbiota. They are simply defined as live microorganisms that, when consumed in adequate amounts confer a health benefit on the host.

The beneficial effects of probiotics in boosting MitoHealth have mainly been studied in neurodegenerative diseases. There is a two-way communication between gut microbes and the central nervous system referred to as gut-brain axis. Thus, changes in gut microbiome is implicated in the pathophysiology of a number of neurodegenerative diseases.

There is a complex connection between gut microbiome, mitochondria, and neurodegenerative disorders.

In a controlled study of induced Alzheimer’s disease in rats, Acidophilus probiotic was able to improve learning and memory by reducing mitochondrial dysfunction probably via antioxidant mechanisms. Gene expression changes in molecules of the mitochondrial permeability complex in hippocampus, a memory consultation centre of the brain, is interesting.

In another model study of Parkinson’s disease, an age-associated condition showed that supplementation of Lactobacillus salivarius  (subspecies salicinius) and its media was neuroprotective to dopaminergic neurons, improved motor functions. These benefits were associated with improved mitochondrial activities in brain and muscle and antioxidant mechanisms. Muscle mass and motor functions (sarcopenia) was restored. Much of these beneficial effects of this probiotic is due to its effects on restoring mitochondrial functions in the brain and muscle as well as reduced ROS levels from its antioxidant mechanisms.

Recommendation: Probiotics are not only for neuroprotection but are beneficial to many tissues and organs of our body as we age.

 

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